Table 3.

The association between TyG index and low cognitive function among nondiabetic older adults

	Low cognitive function assessed by CERAD test				Low cognitive function assessed by Animal Fluency Test				Low cognitive function assessed by DSST
	Crude	Model 1	Model 2		Crude	Model 1	Model 2		Crude	Model 1	Model 2
TyG index (continuous)	1.43 (1.00, 2.04) *	1.50 (0.99, 2.66)	1.61 (1.01, 2.57) *		1.06 (0.68, 1.63)	1.05 (0.68, 1.63)	1.29 (0.71, 2.36)		0.84 (0.57, 1.24)	0.80 (0.52, 1.22)	0.88 (0.46, 1.67)
TyG index (quartiles)
Q1	Reference				Reference				Reference
Q2	1.11 (0.61, 2.00)	1.05 (0.58, 1.89)	0.95 (0.49, 1.82)		1.04 (0.60, 1.79)	1.01 (0.62, 1.66)	1.05 (0.52, 2.10)		0.97 (0.54, 1.37)	0.90 (0.48, 1.67)	0.81 (0.30, 2.16)
Q3	1.43 (0.77, 2.64)	1.27 (0.63, 2.55)	1.20 (0.57, 2.50)		1.30 (0.74, 2.28)	1.21 (0.71, 2.05)	1.32 (0.73, 2.37)		1.34 (0.68, 2.65)	1.18 (0.61, 2.29)	1.21 (0.51, 2.85)
Q4	2.02 (1.12, 3.66) *	2.20 (1.14, 4.26) *	2.62 (1.31, 5.23) *		0.97 (0.49, 1.91)	0.94 (0.48, 1.83)	1.21 (0.49, 3.01)		0.68 (0.35, 1.32)	0.64 (0.32, 1.29)	0.76 (0.29, 1.99)

Abbreviations: The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD); Digit Symbol Substitution Test (DSST)

Data are presented as OR (95% confidence intervals). * P < 0.05. ** P < 0.01

Crude model adjusted for None; Model 1 adjusted for age and gender; Model 2 adjusted for age, gender, BMI, race/ethnicity, educational level, family income-poverty

ratio, serum total cholesterol (mg/dl), physical activity, drinking status, smoking status, hypertension, heart failure, coronary heart disease, and stroke

The CERAD test included CERAD-WL and CERAD-DR.

Low cognitive function was defined the 25th quantile of each cognitive test score of each test as the cutoff point (CERAD: 23; AFT: 15; DSST: 43)