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. 2023 Nov 6;12(11):10. doi: 10.1167/tvst.12.11.10

Figure 3.

Figure 3.

(A) Riboflavin transferred through corneal epithelial cells. DODAP/ISA formulations containing 0.25% or 2.5% riboflavin 5′-phosphate and MedioCROSS were applied to LabCyte, and the concentration of transferred riboflavin was measured using HPLC. Data are shown as average ± SD (n = 3). *P < 0.05, DODAP/ISA (2.5%) versus DODAP/ISA (0.25%); +P < 0.05, DODAP/ISA (2.5%) versus MedioCROSS. **P < 0.05, MedioCROSS versus DODAP/ISA (0.25%). (B) TEER values after incubation of DODAP/ISA formulations containing 0.25% or 2.5% riboflavin 5′-phosphate and MedioCROSS for 24 hours. Data are shown as average ± SD (n = 3). *P < 0.05, DODAP/ISA (2.5% VB2-P) versus MedioCROSS; **P < 0.05, DODAP/ISA (0.25% VB2-P) versus MedioCROSS. VB2-P, riboflavin 5′-phosphate.