Fig. 4.

Effects of sex, IFNγ signaling, and injury on absolute and net microglial movements. (A) Linear regression analysis illustrates the relationship between the absolute movement of microglia over a 24-h period and the original distance from the injured vessel, for both male and female mice (top and bottom rows, respectively). Note that mobile cells are open circles while stable cells are filled circles. (B) Graphs show absolute movement of each mobile microglia in each experimental group over time. (C) Graphs indicate the net movement of mobile microglia. For data in B and C, a three-way ANOVA was used to examine main effects of Sex, Bleed, and IFNγ status at each time point. Data are mean ± SEM.