Table.
Patient Demographics and Nevi Characteristics
| Feature | Pigmented | Mixed | Non-Pigmented |
|---|---|---|---|
| Total number of nevi | 11 (100) | 3 (100) | 3 (100) |
| Average age (SD) | 68 (17) | 84 (6) | 61 (15) |
| Gender | |||
| Male | 5 (45) | 1 (33) | 2 (66) |
| Female | 6 (55) | 2 (66) | 1 (33) |
| Involved eye | |||
| Left | 6 (55) | 3 (100) | 1 (33) |
| Right | 5 (45) | 0 (0) | 2 (66) |
| Ethnicity Caucasian | 11 (100) | 3 (100) | 3 (100) |
| Quadrantic location | |||
| Macula | 2 (18) | 0 (0) | 0 (0) |
| Inferior | 1 (9) | 1 (33) | 1 (33) |
| Temporal | 6 (55) | 1 (33) | 2 (66) |
| Superior | 1 (9) | 1 (33) | 0 (0) |
| Nasal | 1 (9) | 0 (0) | 0 (0) |
| Size measured with non-PD-OCT* | |||
| Basal diameter, mm (SD) | 4.56 (1.36) | 5.65 (0.42) | 6.33 (2.06) |
| Height, mm (SD) | 0.58 (0.11) | 0.57 (0.07) | 1.23 (0.78) |
| Area, mm2 (SD) | 12.49 (6.81) | 16.86 (3.79) | 25.37 (16.43) |
| Subretinal fluid | 4 (33) | 0 (0) | 1 (33) |
| Orange pigment on AF | |||
| Yes | 0 (0) | 0 (0) | 1 (33) |
| No | 9 (82) | 3 (100) | 2 (67) |
| AF not available | 2 (18) | 0 (0) | 0 (0) |
| RPE melanin loss on PD-OCT | |||
| Yes | 6 (55) | 1 (33) | 2 (50) |
| No | 5 (45) | 2 (66) | 1 (50) |
| Mean DOPU (SD) | 0.896 (0.080) | 0.985 (0.017) | 0.994 (0.010) |
| Mean attenuation coefficient (SD) | 1.521 (0.650) | 1.354 (0.421) | 1.117 (0.284) |
| Melanin occupancy, % (SD) | 47.2 (32.9) | 15.6 (18.7) | 6.42 (11.1) |
Pigmentation was determined based on fundus photo appearance. Percentages are written in parentheses, unless otherwise specified.
SD, Standard deviation; AF, autofluorescence; PD-OCT, Polarization-diversity optical coherence tomography; DOPU, degree of polarization uniformity.
*
Size measurement was not possible for two pigmented nevi and one mixed nevus due to incomplete margin acquisition.