Table 3.
Aetiopathological classification | % of childhood dementia births |
---|---|
Inborn errors of metabolism (65.6% of births) | |
Lysosomal disorders (22.4% of births) | |
Lysosomal disorders of lipid metabolism and transport | 10.1 |
Mucopolysaccharidoses | 7.3 |
Glycoproteinosis | 1.4 |
Other lysosomal diseases | 3.6 |
Other disorders of lipid metabolism and transport | 0.7 |
Disorders of amino acid and other organic acid metabolism | 6.7 |
Vitamin-responsive inborn errors of metabolism | 4.8 |
Disorders of mineral absorption and transport | 1.0 |
Peroxisomal disease | 9.5 |
Mitochondrial disorders | 20.3 |
Other inborn errors of metabolism | 0.1 |
Leukodystrophies not otherwise categorized | 6.6 |
Neurodegeneration with brain iron accumulation | 0.6 |
Diseases not otherwise categorised | 27.3 |
Includes 69 conditions with data available, listed in Supplementary Table 1.