Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 12;146(11):4766–4783. doi: 10.1093/brain/awad231

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Assessment of postnatal brain overgrowth in mouse KRD model and human KRD probands. (A) Percentage change in mean of total brain area, motor cortex and hippocampus in Kptn^−/− mutant mice compared to wild-types at birth, 3 weeks and 16 weeks postnatally, with significance level indicated by asterisks in graph. Points without asterisks are not significantly different (P > 0.05, two-tailed Student's t-test). (B) Occipital frontal circumference (OFC) measurements from 15 individuals with KRD from birth (lower bars) to age at last assessment (red dots). Pink shading in B indicates the macrocephalic range, with SD >2.