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Cytotoxicity and in vitro CRIT efficacy of MEP5 and TPP NPs. Cell viability of 4T1 cancer cells was measured by adding (a) MEP5, (b) TPP NPs, or (c) 89Zr-DFO to the culture media at various concentrations or radioactivity levels. (d) CRIT efficacy of MEP5 and TPP NPs was compared at equivalent TPP concentrations when activated by 150 μCi of Zr-89.
