Table 2. Drawbacks of Botox and Anti-CGRP.

Botox: OnabotulinumtoxinA; Anti-CGRP: Calcitonin gene-related peptide antibodies

Table created by author Manoj Pallapothu

Botox	Anti-CGRP
Muscle weakness	Fatigue and constipation
Neck pain	URT symptoms
Eyelid ptosis	Rash and pruritus at the injection site
Costs $3000 every 3 months	Costs up to $600 every month
Effectiveness affected by high BMI	Painful as injected subcutaneously