Table 2.
Laboratory characteristics of patients with DFU between the non-sepsis group and sepsis group.
| Variables | Total (n = 216) |
Non-sepsis group (n = 166) |
Sepsis group (n = 50) |
Value of p |
|---|---|---|---|---|
| WBC (109/L) | 9.08 (6.78, 13.76) | 7.95 (6.56, 9.93) | 14.91 (8.72, 19.84) | <0.001 |
| Hemoglobin (g/dL) | 115 (97.25, 131.75) | 113 (102, 136) | 117 (98, 124) | 0.029 |
| HbA1C (%) | 9.80 (8.10, 11.70) | 9.65 (8.12, 11.40) | 9.80 (7.63, 11.57) | 0.512 |
| GLU (mmol/L) | 8.52 (6.38, 12.92) | 8.24 (5.54, 12.97) | 8.50 (7.72, 11.56) | 0.779 |
| BUN (mmol/L) | 5.6 (4.4, 7.8) | 5.3 (4.3, 8.5) | 6.3 (5.1, 7.7) | 0.101 |
| CRE (μmol/L) | 71.0 (59.3, 92.5) | 74.5 (61.2, 94.3) | 83.0 (62.8, 102.5) | 0.345 |
| INR | 1.02 (0.92, 1.11) | 0.98 (0.92, 1.09) | 1.06 (0.98, 1.15) | <0.001 |
| APTT (s) | 38.2 (34.7, 42.9) | 35.9 (32.5, 41.0) | 40.0 (37.5, 44.8) | <0.001 |
| PT (s) | 13.3 (12.4, 14.3) | 12.8 (12.1, 14.1) | 13.8 (12.9, 14.7) | <0.001 |
| TBIL (μmol/L) | 8.75 (6.03, 13.08) | 8.00 (5.63, 10.83) | 10.60 (5.93, 13.55) | 0.102 |
| DBIL (μmol/L) | 2.7 (1.9, 4.4) | 2.3 (1.7, 4.0) | 3.5 (1.8, 4.0) | 0.007 |
| AST (U/L) | 19 (14, 24) | 20 (15, 28) | 17 (13, 24) | 0.214 |
| ALT (U/L) | 17.5 (12.0, 25.8) | 22.0 (13.8, 30.0) | 13.5 (10.3, 19.8) | 0.312 |
| Sodium (mg/L) | 138.4 (135.5, 140.7) | 139.2 (136.5, 141.4) | 137.4 (134.0, 140.5) | 0.082 |
| Calcium (mg/L) | 2.19 (2.08, 2.31) | 2.24 (2.14, 2.30) | 2.12 (1.93, 2.33) | <0.001 |
| Albumin (g/L) | 31.9 (27.1, 36.5) | 32.8 (27.5, 37.4) | 30.2 (26.8, 33.4) | 0.001 |
| PCT (ng/ml) | 0.14 (0.05, 0.84) | 0.11 (0.05, 0.48) | 0.27 (0.09, 1.75) | <0.001 |
| CRP (mg/L) | 68.2 (10.8, 146.5) | 32.5 (6.7, 93.3) | 156.6 (103.0, 211.7) | <0.001 |
| PLR | 172.75 (115.70, 270.24) | 152.67 (107.15, 237.63) | 276.84 (137.29, 364.00) | <0.001 |
| NLR | 3.91 (2.21, 9.00) | 3.42 (2.08, 6.27) | 10.00 (4.96, 25.84) | <0.001 |
| PNI | 40.13 (32.98, 46.10) | 41.78 (34.20, 47.16) | 35.28 (29.86, 44.75) | <0.001 |
WBC, white blood cell; HbA1c, hemoglobin A1c; BUN, blood urea nitrogen; CRE, creatinine; APTT, activated partial thromboplastin time; PT, thrombin time; INR, international normalized ratio; AST, aspartate aminotransferase; ALT, alanine aminotransferase; PCT, procalcitonin; CRP, C-reactive protein; PLR, platelet-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; PNI, prognostic nutrition index.