Subject	Psychology
Specific subject area	Neuropeptide administration research (Oxytocin (OT) vs. Placebo (PL), Between-subjects) in healthy younger and older women and men; cognitive and neurobiological measures.
Data format	Raw
Type of data	•.tsv files (dataset with labels and numbers) •.json files (descriptions of labels and data in accompanying .tsv/.nii files) •.nii files (BIDS formatted raw and defaced neuroimaging files) •.pdf files (cognitive measures)
Data collection	Data was collected between August 2013 and October 2014. Adults aged 18-31 and 63-81 years were prescreened for study eligibility via phone, during which demographic and cognitive data was collected. Eligible participants then came to the University of Florida (UF) for an in-person screening session during which cognitive data was collected along with blood and saliva samples. Participants returned for an in-person full session during which they self-administered the intranasal spray (OT or PL; randomized, double-blind procedure) and underwent MRI scanning (i.e., T1-weighted structural scan; resting state fMRI scan). Neuroimaging data were collected using a 3T Philips Achieva MRI Scanner.
Data source location	Participants were recruited around the Gainesville area in Florida, USA (GPS coordinates: 29.6446° N, 82.3535° W) and attended study sessions at UF.
Data accessibility	Repository name: OpenNeuro Data identification number: doi:10.18112/openneuro.ds004725.v1.0.1 Direct URL to data:https://openneuro.org/datasets/ds004725/versions/1.0.1 Instructions for accessing these data: Data can be accessed via the above link. Please cite this paper and the OpenNeuro repository for any analyses conducted on this data.
Related research article	P. Liu, T. Lin, D. Feifel, N.C. Ebner, Intranasal oxytocin modulates the salience network in aging, Neuroimage. 253 (2022) 119045. https://doi.org/10.1016/j.neuroimage.2022.119045.