Table 2.
Tumor response with anlotinib in RM-NPC according to RECIST v.1.1
| Responses | FAS (n = 39) | PPS (n = 36) |
|---|---|---|
| Best overall response, no.; % (95% CI) | ||
| CR | 0; 0 (0 to 9.0) | 0; 0 (0 to 9.7) |
| PR | 8; 20.5 (9.3 to 36.5) | 8; 22.2 (10.1 to 39.2) |
| SD | 20; 51.3 (34.8 to 67.6) | 20; 55.6 (38.1 to 72.1) |
| PD | 8; 20.5 (9.3 to 36.5) | 8; 22.2 (10.1 to 39.2) |
| NA | 3; 7.7 (1.6 to 20.9) | 0; 0 (0 to 9.7) |
| ORR, n (%) | 8; 20.5 (9.3 to 36.5) | 8; 22.2 (10.1 to 39.2) |
| DCR, n (%) | 28; 71.8 (55.1 to 85.0) | 28; 77.8 (60.8 to 89.9) |
CR Complete response, DCR Disease control rate, FAS Full analysis set, NA Not assessable, ORR Objective response rate, PD Progressive disease, PPS Per-protocol set, PR Partial response, SD Stable disease