Table 4.
Univariate analysis | Multivariate analysis | |||||||
---|---|---|---|---|---|---|---|---|
HR | P >|z| | 95% CI | HR | P >|z| | 95% CI | |||
TMEM79 expression | ||||||||
High vs low or none | 4.552 | < 0.001a | 3.047 | 6.801 | 3.833 | < 0.001a | 2.520 | 5.831 |
SMG5 expression | ||||||||
High vs low or none | 2.945 | < 0.001a | 1.984 | 4.372 | 1.903 | 0.002a | 1.257 | 2.883 |
Age (years) | ||||||||
≤ 60 vs > 60 | 1.001 | 0.995 | 0.694 | 1.444 | ||||
Gender | ||||||||
Male vs female | 1.183 | 0.373 | 0.818 | 1.712 | ||||
Tumor diameter (cm) | ||||||||
≤ 3 vs > 3 | 1.482 | 0.015a | 1.079 | 2.037 | 1.446 | 0.039a | 1.019 | 2.051 |
AFP (μg/L) | ||||||||
≤ 400 vs > 400 | 1.091 | 0.644 | 0.754 | 1.579 | ||||
Tumor number | ||||||||
Solitary vs multiple | 0.491 | 0.001a | 0.328 | 0.737 | 0.976 | 0.927 | 0.578 | 1.647 |
TNM stage | ||||||||
I vs II vs III + IV | 1.878 | < 0.001a | 1.612 | 2.187 | 1.487 | 0.119 | 0.904 | 2.446 |
T | ||||||||
1 vs 2 vs 3 vs 4 | 2.274 | < 0.001a | 1.839 | 2.813 | 1.338 | 0.179 | 0.875 | 2.044 |
N | ||||||||
0 vs 1 | 2.005 | 0.126 | 0.822 | 4.895 | ||||
M | ||||||||
0 vs 1 | 4.278 | < 0.001a | 2.590 | 7.066 | 0.910 | 0.852 | 0.338 | 2.451 |
Differentiation | ||||||||
Well vs moderate vs poor | 1.211 | 0.146 | 0.936 | 1.566 | ||||
Hepatitis B virus infection | ||||||||
No vs yes | 0.762 | 0.384 | 0.412 | 1.406 | ||||
Vascular invasion | ||||||||
No vs yes | 1.763 | 0.003a | 1.209 | 2.571 | 0.351 | 0.318 | 0.045 | 2.734 |
Liver Cirrhosis | ||||||||
No vs yes | 0.945 | 0.723 | 0.689 | 1.294 | ||||
Recurrence | ||||||||
No vs yes | 1.812 | 0.002a | 1.247 | 2.633 | 1.968 | 0.508 | 0.265 | 14.638 |
HCC hepatocellular carcinoma, HR hazard ratio, CI confidence interval
aP < 0.05 was considered significant