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. 2023 Nov 7;28:490. doi: 10.1186/s40001-023-01388-w

Table 4.

Univariate and multivariable analyses of survival factors in patients with HCC

Univariate analysis Multivariate analysis
HR P >|z| 95% CI HR P >|z| 95% CI
TMEM79 expression
 High vs low or none 4.552  < 0.001a 3.047 6.801 3.833  < 0.001a 2.520 5.831
SMG5 expression
 High vs low or none 2.945  < 0.001a 1.984 4.372 1.903 0.002a 1.257 2.883
Age (years)
  ≤ 60 vs > 60 1.001 0.995 0.694 1.444
Gender
 Male vs female 1.183 0.373 0.818 1.712
Tumor diameter (cm)
  ≤ 3 vs > 3 1.482 0.015a 1.079 2.037 1.446 0.039a 1.019 2.051
AFP (μg/L)
  ≤ 400 vs > 400 1.091 0.644 0.754 1.579
Tumor number
 Solitary vs multiple 0.491 0.001a 0.328 0.737 0.976 0.927 0.578 1.647
TNM stage
 I vs II vs III + IV 1.878  < 0.001a 1.612 2.187 1.487 0.119 0.904 2.446
T
 1 vs 2 vs 3 vs 4 2.274 < 0.001a 1.839 2.813 1.338 0.179 0.875 2.044
N
 0 vs 1 2.005 0.126 0.822 4.895
M
 0 vs 1 4.278 < 0.001a 2.590 7.066 0.910 0.852 0.338 2.451
Differentiation
 Well vs moderate vs poor 1.211 0.146 0.936 1.566
Hepatitis B virus infection
 No vs yes 0.762 0.384 0.412 1.406
Vascular invasion
 No vs yes 1.763 0.003a 1.209 2.571 0.351 0.318 0.045 2.734
Liver Cirrhosis
 No vs yes 0.945 0.723 0.689 1.294
Recurrence
 No vs yes 1.812 0.002a 1.247 2.633 1.968 0.508 0.265 14.638

HCC hepatocellular carcinoma, HR hazard ratio, CI confidence interval

aP < 0.05 was considered significant