Table 2.

Serial changes in quality of life from baseline to the last follow-up visit

Variables		Mean Difference	Z	p-value
Satisfaction	Baseline & visit 1	3.78	-9.79	0.000*
	Baseline & visit 2	6.11	-11.76	0.000*
	Baseline & visit 3	7.92	-12.78	0.000*
Impact	Baseline & visit 1	2.32	-7.90	0.000*
	Baseline & visit 2	3.95	-10.56	0.000*
	Baseline & visit 3	5.20	-12.04	0.000*
Worry	Baseline & visit 1	1.68	-8.24	0.000*
	Baseline & visit 2	2.83	-10.66	0.000*
	Baseline & visit 3	3.70	-12.00	0.000*
Total	Baseline & visit 1	7.77	-9.87	0.000*
	Baseline & visit 2	12.89	-11.78	0.000*
	Baseline & visit 3	15.24	-11.62	0.000*

The Wilcoxon Signed Ranks test is applied to observe the mean change in QoL from baseline to follow-up (Non-parametric data). *p < 0.05 is considered statistically significant. Z based on positive ranks