Table 2.
Effect on anthropometrics and HOMA-IR
| Study Group | No. of Studies/Subgroups | Heterogeneity | Effects Estimate (95% CI) | P value |
|---|---|---|---|---|
| BMI (WMD) | 9 | P = 0.147, I2 = 31.5% | -1.21 (-1.74, -0.68) | P < 0.001 |
| GLP1RA + MET vs MET | 3 | P = 0.825, I2 = 0% | -0.71 (-2.15, 0.73) | P = 0.335 |
| GLP1RA vs MET | 7 | P = 0.218, I2 = 27.6% | -1.05 (-1.69, -0.42) | P = 0.001 |
| GLP1RA vs Placebo | 1 | Not Applicable | -2.00 (-2.79, -1.21) | P < 0.001 |
| WC (WMD) | 9 | P = 0.470, I2 = 0% | -2.90 (-3.65, -2.16) | P < 0.001 |
| TBF (WMD) | 5 | P = 0.003, I2 = 72.5% | -1.44 (-2.93, 0.05) | P = 0.058 |
| European | 5 | P = 0.772, I2 = 0% | -1.84 (-4.60, 0.92) | P < 0.001 |
| Chinese | 1 | Not Applicable | -1.30 (-1.73, -0.87) | P < 0.001 |
| HOMA-IR (WMD) | 10 | P = 0.573, I2 = 0% | -0.65 (-0.80, -0.51) | P < 0.001 |