TABLE 2.
Characteristics of CUD patients in the ketamine treatment or other anesthetic treatment cohorts before and after propensity scorematching.
| Characteristics | Before matching |
After matching |
||||
|---|---|---|---|---|---|---|
| Ketamine cohort | Anesthetic cohort | SMD | Ketamine cohort | Anesthetic cohort | SMD | |
|
| ||||||
| Total no. | 3872 | 13 868 | 3871 | 3871 | ||
| Age, mean (SD) | 43.2 (13.1) | 47.6 (13.1) | 0.33 | 43.2 (13.1) | 42.7 (13.5) | 0.04 |
| Sex, % | ||||||
| Female | 36.6 | 36.4 | 0.005 | 36.6 | 35.6 | 0.02 |
| Male | 63.4 | 63.6 | 0.005 | 63.4 | 64.4 | 0.02 |
| Ethnicity, % | ||||||
| Hispanic/Latinx | 9.9 | 7.5 | 0.09 | 9.9 | 9.6 | 0.01 |
| Not Hispanic/Latinx | 81.4 | 81.6 | 0.005 | 81.4 | 82.1 | 0.02 |
| Race, % | ||||||
| African American/Black | 31.8 | 44.5 | 0.26 | 31.8 | 32.5 | 0.01 |
| White | 59.1 | 47.7 | 0.23 | 59.1 | 58.7 | 0.01 |
| Asian | 0.4 | 0.2 | 0.03 | 0.4 | 0.3 | 0.02 |
| Comorbidities, % | ||||||
| Mental and behavioral disorders | 88.9 | 84.6 | 0.13 | 88.9 | 87.8 | 0.04 |
| Mood disorders | 49.7 | 43.3 | 0.13 | 49.7 | 47.1 | 0.05 |
| Anxiety | 48.6 | 39.6 | 0.18 | 48.6 | 46.4 | 0.05 |
| Schizophrenia | 15.9 | 13.1 | 0.08 | 15.9 | 14.4 | 0.04 |
| Hypertensive diseases | 44.9 | 52.9 | 0.16 | 44.9 | 42.9 | 0.04 |
| Ischemic heart diseases | 22.8 | 26.5 | 0.09 | 22.8 | 20.6 | 0.05 |
| Other forms of heart disease | 48.8 | 44.6 | 0.09 | 48.8 | 46.1 | 0.05 |
| Cerebrovascular diseases | 19.5 | 20.3 | 0.02 | 19.5 | 17.8 | 0.04 |
| Acute kidney failure | 21.9 | 19.4 | 0.06 | 21.9 | 20.7 | 0.03 |
| Antisocial personality disorder | 1.3 | 0.8 | 0.04 | 1.3 | 1.2 | 0.01 |
| Conduct disorder | 9.9 | 6.8 | 0.11 | 9.9 | 9.3 | 0.02 |
| ADHD | 5.5 | 3.6 | 0.09 | 5.5 | 4.9 | 0.02 |
| Socio-economic and psychosocial status | 27.9 | 23.3 | 0.11 | 27.9 | 26.1 | 0.04 |
Note: Values shown in bold type are significant at SMD > 0.1.
Abbreviation: ADHD, attention-deficit/hyperactivity disorder; CUD, cocaine use disorder; SMD, standardized mean difference.