Skip to main content
letter
. 2023 Aug 16;43(11):1275–1279. doi: 10.1002/cac2.12478

FIGURE 1.

FIGURE 1

Testing and validation of mSEPT9 and mRNF180 in the validation cohort. (A, B) Methylation levels of RNF180 and SEPT9 in the plasma by the disease status in the prospective validation cohort. Dot plots illustrating DNA methylation levels of subjects with gastric neoplastic lesions or non‐neoplastic disease (mRNF180 and mSEPT9, respectively) are shown; (C) ROC curve analysis of mSEPT9, mRNF180, and the RS9 panel in GA patients and controls; (D) Diagnostic performance of mSEPT9, mRNF180, and the RS9 panel in GA patients and controls. Abbreviations: AG, atrophic gastritis; AUC, area under the curve; Ct, threshold cycle; DE, diagnostic efficiency; GA, gastric adenocarcinoma; GP, gastric polyp; IM, intestinal metaplasia; NA, not available; Non‐AG, non‐atrophic gastritis; NPV: negative predictive value; PPV: positive predictive value.