Figure 1.

Pedigree indicating affected family members. Individuals II-1, III-2, and III-3 developed pterygium in the early 20s, and at 6, and 4 years of age, respectively (fully-shaded symbols). Individuals II-1 and III-3 had a unilateral pterygium, whereas bilateral pterygium was seen in III-2. Individual II-3 was declared legally blind from central corneal scarring with associated peripheral vascularization, and III-6 had severe visual impairment due to dense corneal opacity in the left eye (half-shaded symbols). Individuals II-1, II-3, and III-3 were included in this study. The clinical data are summarized in the supplementary materials (Supplementary Table S1).