Table 2.
Haplotype analysis of V167I carriers on the basis of eight common SNPs in 5088 samples
| Background Haplotypea | V167I Carriers | Noncarriers | Overall Background Haplotype Frequency, % | ||
|---|---|---|---|---|---|
| Total | Frequency, % | % Carriers | |||
| GACTGCCC | 102 | 1.002 | 85.0 | 447 | 5.40 |
| GACTGCTT | 2 | 0.020 | 1.7 | 3 | 0.049 |
| GACTACCC | 5 | 0.049 | 4.2 | 2003 | 19.7 |
| AGTCGCCC | 3 | 0.029 | 2.5 | 529 | 5.2 |
| AGTCACCC | 8 | 0.079 | 6.7 | 1258 | 12.4 |
a
Haplotypes phased from rs699946, rs833068, rs833069, rs3025010, rs3025033, rs3025035, rs6900017, and rs12204488 in 5088 samples (1397 IgA nephropathy and 3691 controls) using the PHASE tool. V167I is located between the fourth and fifth SNPs (rs3025010 and rs3025033).