Table 2.

Pathophysiology of electrolyte disorders in primary mitochondrial diseases

Pathophysiologic Mechanism	No. of Patients (% of Total)
Hypoparathyroidism	55 (15)
Hyperparathyroidism	9 (2)
Proximal tubulopathy	46 (13)
Bartter/Gitelman-like tubulopathy	33 (9)
Syndrome of inappropriate antidiuretic hormone secretion	8 (2)
Disturbed renin and/or aldosterone	24 (7)
Urinary electrolyte values consistent with renal wasting	72 (20)
Gastrointestinal (e.g., diarrhea or vomiting)	79 (22)

Pathophysiologic mechanisms reported in the case reports and case series. Percentages reflect the number of patients in which a mechanism was reported compared with the total number of included patients. Percentages do not take into account in how many patients the item was measured.