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. 2023 Nov 8;18(11):e0289863. doi: 10.1371/journal.pone.0289863

Fig 1. Generation and screening of PK-15 cells lacking Ifnar1 or Stat2.

Fig 1

Normal PK-15 cells, PK-15 Ifnar1 k/o cells, or PK-15 Stat2 k/o cells treated with various concentrations of pig IFNβ were infected with HIV-1–based reporter virus. Infectivity was calculated as relative light units (RLU) 2 days after infection. Relative infectivity was calculated in comparison that in untreated cells. The results are presented as the mean and standard deviation of quadruplicate measurements from one assay, and they are representative of at least three independent experiments. Differences were examined by one-way ANOVA followed by Tukey’s test. ****p < 0.0001.