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. 2023 Nov 8;18(11):e0289863. doi: 10.1371/journal.pone.0289863

Fig 4. PK-15 cells lacking Ifnar1 or Stat2 exhibit susceptibility to viral infection in the presence of poly (I:C).

Fig 4

The replication of IAV (a) and AKAV (b) was examined in normal PK-15, PK-15 Ifnar1 k/o, and PK-15 Stat2 k/o cells. Before infection, the cells were transfected with 0 or 100 ng/mL poly (I:C). Viral RNA levels in the culture supernatant were quantified via qRT–PCR 2 days after viral infection. The relative values were calculated with respect to non-pretreated cells. The results are presented as the mean and standard deviation of eight repeated measurements from one assay. Differences between 100 ng/mL poly (I:C)-treated cells and untreated cells were examined via a two-tailed, unpaired Student’s t-test. ****p < 0.0001, **p < 0.01, and *p < 0.05, ns (not significant).