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. 2023 Nov 8;3(11):e0002261. doi: 10.1371/journal.pgph.0002261

Table 1. Characteristics for neonates with birth asphyxia by birth location.

All patients
(N = 1,565)
n (%)
Inborn
(N = 803)
n (%)
Outborn
(N = 762)
n (%)
Maternal Demographics
Mother’s age (years) (n = 1374)
    <20 330 (24.0) 145 (22.0) 185 (25.9)
    20–35 942 (68.6) 460 (69.8) 482 (67.4)
    >35 102 (7.4) 54 (8.2) 48 (6.7)
Gravida (n = 1474)
    1 (primigravid) 612 (45.5) 292 (39.1) 320 (44.0)
    2–3 494 (33.5) 256 (34.3) 238 (32.7)
    ≥ 4 368 (25.0) 199 (26.6) 169 (23.3)
Antenatal care visits (n = 1302)
    0 3 (0.2) 3 (0.4) 0 (0.0)
    1–3 564 (43.3) 289 (45.2) 275 (41.5)
    ≥ 4 735 (56.5) 348 (54.4) 387 (58.5)
Maternal district (n = 1565) *
    Within KH district 578 (36.9) 327 (40.7) 251 (32.9)
    Outside KH district 987 (63.1) 476 (59.3) 511 (67.1)
Mode of transport (n = 1565) (maternal) (newborn) **
    Ambulance 334 (21.3) 78 (9.7) 256 (33.6)
    Another vehicle 1096 (70.0) 607 (75.6) 489 (64.2)
    Bicycle or foot 135 (8.6) 118 (14.7) 17 (2.2)
At Birth
Type of birth attendant (n = 1565) **
    Doctor 511 (32.6) 379 (47.2) 132 (17.3)
    Midwife/nurse 1035 (66.1) 422 (52.6) 613 (80.5)
    TBA, family member or other 19 (1.2) 2 (0.2) 17 (2.2)
Mode of delivery (n = 1565) **
    Vaginal 1083 (69.2) 441 (54.9) 642 (84.2)
    Caesarean section 482 (30.8) 362 (45.1) 120 (15.8)
Meconium-stained fluid (n = 1039) **
    No 585 (56.3) 333 (51.5) 252 (64.1)
    Yes 454 (43.7) 313 (48.5) 141 (35.9)
Cried at birth (n = 1388)
    No 1146 (82.6) 581 (72.3) 565 (83.2)
    Yes 242 (17.4) 128 (15.9) 114 (16.8)
Apgar—median [IQR]
    1 minute (n = 1227) 5 (4–6) 5 (4–6) 6 (5–7)
    5 minute (n = 1202) 6 (5–8) 6 (5–7) 7 (5–8)
Infant characteristics
Sex (n = 1565)
    Female 608 (38.8) 314 (39.1) 294 (38.6)
    Male 957 (61.2) 489 (60.9) 468 (61.4)
Multiple birth (n = 1560) *
    Singleton 1488 (95.4) 754 (94.1) 734 (96.7)
    Multiple birth 72 (4.6) 47 (5.9) 25 (3.3)
Age at admission (days) (n = 1565) **
    Day of birth 1410 (90.1) 793 (98.7) 617 (81.0)
    1–2 days of age 141 (9.0) 6 (0.8) 135 (17.7)
    3+ 14 (0.9) 4 (0.5) 10 (1.3)
Birthweight (n = 1546)
    < 2.5kg 162 (10.5) 91 (11.4) 71 (9.5)
    2.5–4.49kg 1369 (88.5) 703 (87.9) 666 (89.3)
    4.5kg+ 15 (1.0) 6 (0.8) 9 (1.2)
Admission Vital Signs
Temperature (°C) (n = 1537) **
    < 36.5 898 (58.4) 604 (76.7) 294 (39.2)
    36.5–37.9 480 (31.2) 179 (22.7) 301 (40.1)
    ≥ 38 159 (10.3) 4 (0.5) 155 (20.7)
Respiratory rate (bpm) (n = 1379)
    < 30 42 (3.1) 22 (3.1) 20 (3.0)
    30–60 638 (46.3) 350 (49.4) 288 (43.0)
    > 60 699 (50.7) 337 (47.5) 362 (54.0)
Oxygen saturation (%) (n = 1417)
    < 90 556 (36.2) 298 (41.5) 258 (36.9)
    ≥ 90 861 (60.8) 420 (58.5) 441 (63.1)
Blood sugar (mmol/L) (n = 1441) *
    < 2.6 96 (6.7) 39 (5.2) 57 (8.2)
    2.6–8.3 1058 (73.4) 546 (73.0) 512 (73.9)
    >8.3 287 (19.9) 163 (21.8) 124 (17.9)
Clinical Course
Therapies received:
    Phototherapy (n = 1545) 283 (18.3) 130 (16.3) 153 (20.4) *
    Blood transfusion (n = 1555) 22 (1.4) 11 (1.4) 11 (1.4)
    Bubble CPAP (n = 1543) 277 (18.0) 110 (13.9) 167 (22.2) **
Died during admission 339 (21.7) 103 (12.8) 236 (31.0) **

*p <0.05

** <0.001