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. 2023 Nov 8;9(45):eadh0708. doi: 10.1126/sciadv.adh0708

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Fig. 4. — Pan-virus serological profile (VirScan) was assessed in sera of 176 patients with aNSCLC. (A and B) Among 117 CMV⁺ patients, the number of recognized CMV peptides is represented between T₈sen^high and T₈sen^low patients (A) and according to the proportion of CD8⁺ senescent T cells among CD8⁺ (B). (C) Proportion of CD8⁺ senescent T cells depending on the presence of antibodies targeting IRS1, gB, gp58, and US20 among CMV⁺ patients in the VirScan cohort. (D) Proportions of T₈sen^high and T₈sen^low patients depending on each protein’s seropositivity in CMV⁺ patients. (E) Proportions of IRS1-, gB-, gp58-, and US20-positive patients according to T₈sen status in CMV⁺ patients. Categorical variables were compared by Fisher test; continuous variables were compared in two populations by Mann-Whitney t test, and two continuous variables were compared using Spearman correlation.