Table 1.

some representative microorganisms producing paclitaxel.

Genera	Endophyte	Host	Paclitaxel Yield(μg/L)	Methods of Optimization	Final yield (μg/L)	Reference
Alternaria	Alternaria alternata MF5	Taxus	5700	-	-	[19]
	Alternaria brassicicola MVR1	Terminalia arjuna	140.8			[24]
	Alternaria tenuissima TER995	Taxus arjuna	37.92	Bioprocess optimization	124.32	[31]
Annulohypoxylon	Annulohypoxylon sp.	Taxus wallichiana Zucc.	282.05	–	–	[32]
	Aspergillus flavipes ATCC 24,487	Rhizosphere	185	Addition of fluconazole (1.0 μg/ml) or P. gracilior leaf (0.5 g)	320/210	[33]
Aspergillus	Aspergillus flavus MW485934.1	jojoba	88.6	Bioprocess optimization and γ-irradiation	375.9	[34]
	Aspergillus fumigatus TXD105	Tsxus distichum	84.41	Bioprocess optimization	307.03	[31]
	Aspergillus fumigatus	Taxus sp.	1590	-	-	[6]
	Aspergillus oryzae	Tarenna asiatica	95.04	–	–	[35]
	Aspergillus terreus EFB108	Podocarpus gracilior	114.2	Physicochemical optimization and addition of surface-sterilized P. gracilior leaves	432	[23]
Cladosporium	Cladosporium cladosporioides MD2	Taxus media	800	–	–	[36]
	Cladosporium sphaerospermum AUMC 6896	Clover leaf weevil	3.732	Adding ammonium acetate (20 mg/L)	30.365	[37]
Epicoccum	E. nigrum TXB502	Taxus baccata	61.35	Bioprocess optimization, γ-irradiation and immobilization	1364.63	[38]
	Fusarium redolens	Taxus brevifolia	70	Bioprocess optimization	198	[39]
Fusarium.	Fusarium solani Tax-3	Taxus chinensis	163.35	–	–	[18]
Grammothele	Grammothele lineata SDL-CO-2015-1	Corchorus olitorius	382.2	–	–	[22]
Lasiodiplodia	Lasiodiplodia theobromae SKJM1101	Piper nigrum	247	–	–	[40]
Metarhizium	Metarhizium anisopliae H-27	Taxus chinensis	846.1	–	–	[17]
Metarizium	Metarizium anisopliae AUMC 5130	clover leaf weevil	0.0023	Adding both ammonium acetate (20 mg/L) and Salicylic acid (90 mg/L)	116.373	[37]
Nodulisporium	Nodulisporium sylviform HQD33	Taxus cuspidate	51.06–125.70	Strain improving	516.37	[41]
Penicillium	Penicillium chrysogenum R16	Glycin max	170	Bioprocess optimization	250	[26]
	Penicillium polonicum AUMC14487	Ginko biloba	90.53	Bioprocess optimization and γ-irradiation	401.2	[25]
Pestalotiopsis	Pestalotiopsis hainanensis	Ailuropoda melanoleuca	1466.87	-	-	[7]
Pestalotiopsis	Pestalotiopsis microspora	Taxodium mucronatum	283.11	Addition of Salicylic acid(300 μM)	625.47	[42]
Phoma	Phoma medicaginis	Taxus wallichiana var. mairei	1215	–	–	[43]