Table 3.

Associations between quantitative blood cell counts and mCA phenotypes

Trait	Test	β	SE	P value	n
WBC	Autosomal	0.0180	0.00281	1.46 × 10−10	49,353
WBC	Autosomal, high CF Yes–Noa	0.0266	0.00373	1.10 × 10−12	49,353
NEU	ChrX	−0.0215	0.00458	2.74 × 10−6	18,415
NEU	ChrX, adjusted for Duffy	−0.0155	0.00442	4.47 × 10−4	18,415
NEU%	ChrX	−0.0246	0.00314	5.12 × 10−15	16,248
NEU%	ChrX, adjusted for Duffy	−0.0242	0.00300	8.87 × 10−16	16,248
LYM	Autosomal	0.0246	0.00467	1.41 × 10−7	33,927
LYM	ChrX	0.0301	0.00371	5.81 × 10−16	19,658
LYM	Autosomal, high CF Yes–Noa	0.0359	0.00638	1.77 × 10−8	33,927
LYM%	ChrX	0.0222	0.00243	8.11 × 10−20	17,245

^aHigh CF mCA was defined as having estimated CF ≥0.03.

CF, clonal fraction; LYM, lymphocytes; NEU, neutrophils; SE, standard error; WBC, white blood cell counts.