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. 2023 Apr 24;46(12):2459–2469. doi: 10.1007/s40618-023-02098-0

Table 3.

Reference interval of FT3 (pmol/L)

First trimester Second trimester Third trimester Post-partum
Sample size 139 139 139 55
Mean + 2SD
 Lower limit 3.88 3.61 3.59 4.18
 90% CI 3.73–4.02 3.53–3.71 3.51–3.67 4.04–4.33
 Upper limit 6.05 5.38 5.37 6.33
 90% CI 5.92–6.17 5.25–5.50 5.23–5.52 6.04–6.66
Percentile non parametric method
 Lower limit 3.74 3.53 3.49 3.97
 90% CI 3.46–4.09 3.32–3.72 3.36–3.75 –*
 Upper limit 6.06 5.54 5.48 6.71
 90% CI 5.84–6.64 5.13–5.74 5.22–5.71 –*
Robust method
 Lower limit 3.87 3.61 3.58 4.16
 90% CI 3.71–4.0 3.51–3.70 3.50–3.66 4.00–4.34
Upper limit 6.06 5.39 5.39 6.41
 90% CI 5.94–6.20 5.26–5.52 5.23–5.54 6.06–6.76

–*Not calculated, as recommended by CLSI document EP28-A3c [16]