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. 2023 Aug 28;270(12):6010–6020. doi: 10.1007/s00415-023-11952-3

Table 1.

Characteristics of the study population and results from cerebrospinal fluid analysis (607 patients)

MS CIS OIND NIND
N 179 116 94 218

Female

N (%)

107 (59.8) 85 (72.4) 52 (55.3) 121 (55.5)

Age at diagnosis

mean ± SD

40.0 ± 13.1 38.9 ± 14.3 43.1 ± 11.2 61.3 ± 9.8

IgG OCB

N (%)

141 (78.8) 72 (62.1) 12 (12.8) 3 (1.4)
IgG index (median, IQR) 0.68 (0.56–0.88) 0.59 (0.51–0.84) 0.52 (0.47–0.60) 0.48 (0.44–0.51)
κFLC index (median, IQR) 28.19 (9.81–61.52) 21.84 (6.52–56.19) 1.94 (1.37–4.63) 1.67 (1.36–2.28)

MS multiple sclerosis, CIS clinically isolated syndrome, OIND other inflammatory neurological diseases, NIND not inflammatory neurological diseases, OCB oligoclonal bands, IQR interquartile range, κFLC kappa free light chains