Table 5.

Paired comparison between AUCs of CSF IgG OCB and different κFLC index thresholds for the diagnosis of MS/CIS in our study population (607 patients)

IgG OCB-κFLC	z	p	Delta AUC	95% CI
				Lower limit	Upper limit
4.25	− 2.725	0.006	− 0.038	− 0.065	− 0.011
5.0	− 3.153	0.002	− 0.042	− 0.068	− 0.016
5.90	− 2.656	0.008	− 0.033	− 0.058	− 0.009
6.60	− 2.262	0.024	− 0.028	− 0.052	− 0.004
7.83	− 1.744	0.081	− 0.021	− 0.044	0.003
10.5	0.263	0.792	0.003	− 0.021	0.028
11.0	0.410	0.682	0.005	− 0.020	0.030
12.3	0.851	0.395	0.010	− 0.014	0.035

Bold values indicate the statistically significant p values

κFLC kappa free light chains, AUC area under the curve, CI confidence interval