Table 2.
Multivariable analysis of variables explaining MSU crystal volume percentage change measured with DECT over time
| Explanatory variable | Percentage of remaining MSU crystal volume (cm3) (mean (SD)) | Multilevel coefficient (95% CI) | P value | |
| Time since baseline DECT scan (days) | (0.0, 822.0) | 43.5 (41.0) | −0.06 (−0.08 to −0.03) | <0.001 |
| Age (years) | (38.7, 88.6) | 43.5 (41.0) | −0.52 (−1.53 to 0.49) | 0.34 |
| Hypertension | No (reference) | 31.6 (33.3) | – | |
| Yes | 47.1 (42.6) | 41.87 (16.38 to 67.18) | <0.01 | |
| Chronic heart disease | No (reference) | 48.1 (44.2) | – | |
| Yes | 37.9 (36.4) | −19.64 (−44.5 to 5.4) | 0.15 | |
| Serum urate level at follow-up DECT scan (mg/dL) | ≥6.0 (reference) | 82.5 (67.7) | – | |
| <5.0 | 30.3 (32.1) | −39.46 (−70.93 to −8.34) | 0.02 | |
| 5.0 to <6.0 | 73.4 (29.8) | −4.62 (−39.54 to 30.27) | 0.80 |
DECT, dual-energy computed tomography; eGFR, estimated glomerular filtration rate (CKD-EPI formula); MSU, monosodium urate.