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Kaplan-Meier survival curves showing the probability of cardiovascular disease (CVD)–related mortality per quartile of hypoxic burden (left) and oxygen desaturation–based hypoxic burden (right). CVD was based on the underlying cause of death assessed by a study physician adjudicator. A CVD cause of death was broadly categorized by International Classification of Diseases, 9th Revision codes as CVD (codes 396.9–442, 966.71, and 785.51). HBOxi = oximetry-derived hypoxic burden.
