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| Methods | RCT | |
| Participants | surgically resected colorectal cancer | |
| Interventions | HCFU per os 8 mg/kg/d for 3 months versus 12 months | |
| Outcomes | RFS and OS | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Adequate sequence generation? | Low risk | Centralized registration |
| Allocation concealment? | Low risk | randomisation in one centre |
| Blinding? All outcomes | High risk | |
| Free of other bias? | High risk | |
