The interactions formed between best docked 3b and active site epidermal growth factor receptor tyrosine kinase (PDB ID: 1M17).
Residues | Interaction/residue type | Distance (Å) |
---|---|---|
Leu 694 | π-sigma | 3.98 |
Leu 768, Leu 820 | Alkyl | 5.12, 4.76 |
Ala 719, Lys 721 | π-alkyl | 4.85, 5.19 |
Pro 770, Thr 830 | Hydrogen bond | 2.51, 3.44 |
Met 742 | Pi-sulfur | 5.53 |
Met 769 | Conventional H-bond | 2.98 |
Thr 766 | Conventional H-bond | 2.84 |