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. 2023 Nov 9;13(47):33080–33095. doi: 10.1039/d3ra06189b

The interactions formed between best docked 3b and active site epidermal growth factor receptor tyrosine kinase (PDB ID: 1M17).

Residues Interaction/residue type Distance (Å)
Leu 694 π-sigma 3.98
Leu 768, Leu 820 Alkyl 5.12, 4.76
Ala 719, Lys 721 π-alkyl 4.85, 5.19
Pro 770, Thr 830 Hydrogen bond 2.51, 3.44
Met 742 Pi-sulfur 5.53
Met 769 Conventional H-bond 2.98
Thr 766 Conventional H-bond 2.84