Table 3.
Dosimetric and volumetric parameters between groups according to left lung volume
| BCS group (n = 56) | p* | Mastectomy group (n = 58) | ||||
|---|---|---|---|---|---|---|
| ≤ 1154 cc median (min–max) | > 1154 cc median (min–max) | ≤ 1208 cc median (min–max) | > 1208 cc median (min–max) | p* | ||
| PTV volume (cc) | 1178.2 (450.4–2273.0) | 1162.9 (417.7–2060.0) | 0.793 | 659.9 (188.4–1239.0) | 474.6 (234.9–1040.8) | 0.034 |
| PTV min (Gy) | 30.5 (9.5–40.1) | 29.2 (10.6–49.7) | 0.974 | 36.0 (13.6–50.4) | 36.0 (20.1–50.4) | 0.486 |
| PTV max (Gy) | 63.3 (53.8–69.0) | 62.2 (51.6–66.6) | 0.026 | 55.7 (51.5–64.9) | 55.5 (53.2–65.3) | 0.712 |
| PTV mean (Gy) | 52.3 (49.9–55.7) | 51.7 (41.5–62.1) | 0.206 | 51.1 (48.9–53.4) | 51.4 (49.0–57.2) | 0.100 |
| Left lung volume (cc) | 1056.5 (759.7–1164.0) | 1244.4 (1171.5–1564.3) | 0.000 | 1047.4 (740.7–1205.0) | 1346.4 (1211.1–2241.0) | 0.000 |
| Lung min (Gy) | 0.5 (0.1–1.0) | 0.6 (0.1–2.7) | 0.941 | 0.3 (0.1–3.4) | 0.2 (0.0–0.9) | 0.019 |
| Lung max (Gy) | 55.4 (48.7–66.4) | 53.0 (47.3–61.4) | 0.054 | 53.6 (50.1–66.6) | 54.4 (49.8–58.1) | 0.061 |
| Lung mean (Gy) | 13.2 (5.1–20.8) | 11.7 (5.8–17.8) | 0.511 | 15.6 (7.9–20.6) | 15.3 (3.8–51.1) | 0.911 |
| Lung V5 (%) | 40.2 (12.1–64.3) | 36.3 (20.5–60.8) | 0.651 | 44.0 (11.0–65.2) | 41.1 (12.7–53.6) | 0.100 |
| Lung V10 (%) | 30.5 (11.3–57.6) | 29.7 (12.8–49.9) | 0.628 | 37.0 (9.0–50.2) | 34.5 (8.5–42.9) | 0.335 |
| Lung V20 (%) | 25.8 (7.9–49.1) | 22.5 (8.78–37.1) | 0.501 | 30.0 (7.0–42.8) | 29.0 (5.7–37.0) | 0.381 |
| Heart volume (cc) | 674.1 (516.4–1064.1) | 675.5 (466.3–996.4) | 0.588 | 620.6 (441.1–848.1) | 599.3(499.7–821.8) | 0.898 |
| Heart min (Gy) | 0.8 (0.3–16.9) | 0.8 (0.3–45.0) | 0.571 | 0.4 (0.2–40.0) | 0.3 (0.1–1.0) | 0.009 |
| Heart max (Gy) | 52.0 (12.5–58.5) | 50.0 (42.1–58.0) | 0.015 | 51.0 (5.55–54.6) | 51.8 (48.3–53.9) | 0.214 |
| Heart mean (Gy) | 6.2 (2.6–10.2) | 4.5 (2.1–9.1) | 0.001 | 7.1 (4.2–916.2) | 4.5 (2.5–8.0) | 0.000 |
| Heart V10 (%) | 12.3 (2.2–37.0) | 8.8 (4.0–20.0) | 0.007 | 16.0 (9.5–38.0) | 11.7 (6.0–20.0) | 0.006 |
| Heart V25 (%) | 8.2 (0.1–50.0) | 5.6 (2.4–18.0) | 0.020 | 11.0 (5.2–32.0) | 8.0 (3.5–17.0) | 0.002 |
| Heart V35 (%) | 5.6 (0.5–30.0) | 4.0 (1.7–16.0) | 0.036 | 8.1 (1.9–28.0) | 7.0 (2.4–15.0) | 0.017 |
BCS: Breast-conserving surgery, PTV: Planning target volume, n: number of patients, Gy: Gray, cc: cubic centimeter, max: maximum, min: minimum
*Kruskal–Wallis test
Bold values indicate the significant p values (p<0.05)