Fig. 1.

Scatterplot and linear associations between the triglyceride (TG) polygenic risk score (TG-PRS) and TG levels for n = 149 adults with a 22q11.2 microdeletion by obesity classification. Fitted lines were generated using linear regression performed within two sub-groups, with (orange) (beta = 0.4617) and without (blue) (beta = 0.1778) obesity defined as BMI ≥ 30 kg/m² (unadjusted TG x BMI interaction beta = 0.179, p = 0.045). TG levels are natural log (2ln) transformed. The dashed black line indicates the natural log transformed value of the lower-bound clinical cut-off that defines mild-moderate HTG (1.7 mmol/L), thus above this line individuals would be classified as having mild-moderate hypertriglyceridemia