Fig. 1.
Infectious viral titres and CT values for unvaccinated versus vaccinated individuals infected with Delta variant. (a) Viral RNA (CT) versus vaccination status. Data are summarized by boxplots and overlaid with points representing individual subjects. The y axis is flipped for visualization as CT values are inversely proportional to the amount of viral RNA. (b) Viral titre (f.f.u. ml–1) by vaccination status. Data are summarized by boxplots and overlaid with points representing individual subjects. Dashed line indicates the limit of detection for infectious titer (10 f.f.u. ml–1). (c) Viral RNA (CT) on the x axis plotted against viral titre (f.f.u. ml–1) on the y axis. Separate linear regression lines (ŷ = β0 + β1x̄ + Ɛ) were fit to unvaccinated and vaccinated individuals. Shading indicates confidence interval (0.95) for each line. (a−c) Red symbols and lines indicate unvaccinated individuals (N = 12), blue symbols and lines indicate vaccinated individuals (N = 76). Thermocycler method is indicated by shape (Cobas circles, non-Cobas triangles). f.f.u. stands for focus forming unit.