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[Preprint]. 2023 Nov 1:2023.10.27.564454. [Version 1] doi: 10.1101/2023.10.27.564454

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Figure 4. — (A) B cell frequencies as percentage of all CD45⁺ in healthy controls (n=17) and all patients (n=28) before and after treatment. (B) Volcano plot showing differences in absolute counts of 28 cell subsets before and after treatment (n=28). (C–D) Selected comparisons from (B). (E) Heatmap showing median frequencies of key NK cell subsets as percentage of bulk NK cells in healthy controls (n=17) and patients (n=28) before and after therapy. (F) Heatmap showing differences in marker expression within multiple immune cell subsets between patients before and after treatment (n=20–28), with colors indicating direction of difference and statistical significance from paired nonparametric tests without p value adjustment. (G) Mean CD38 expression in multiple NK cell subsets of healthy controls (n=15–17) and patients (n=25–28) before and after treatment.