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[Preprint]. 2023 Nov 2:2023.10.30.564834. [Version 1] doi: 10.1101/2023.10.30.564834

Table 1.

Ionic Channel Parameters.

Channel Parameters
INa gNa = 150 nS ENa = 26.54 · ln(Naout/Nain) Nain = 15 mM Naout = 120 mM
m1/2 = −43.8 mV km = 6.0 mV τmaxm=0.25ms τ1/2m=43.8mV kτm=14.0mV
h1/2 = −67.5 mV kh = −11.8 mV τmaxh=8.46ms τ1/2h=67.5mV kτh=12.8mV
Ik gK = 220 nS Ek = 26.54 · ln(Kbath/Kin) Kin = 125 KBath = 8.5 mM
Aα = 0.011 Bα = 44.0 mV kα = 5.0 mV
Aβ = 0.17 Bβ = 49.0 mV kβ = 40.0 mV
ISPK gSPK = Variable
m1/2 = mV km = mV τmaxm=ms τ1/2m=mV kτm=14.0mV
h1/2 = −67.5 mV kh = −11.8 mV τmaxm=8.46ms τ1/2h=67.5mV kτh=12.8mV
IAHP gAHP = Variable
m1/2 = mV km = mV
INaP gNaP = N(μNaP, σNap) μNaP = 3.33 nS σNaP = 0.75 nS
m1/2 = −47.1 mV km = 3.1 mV τmaxm=1.0ms τ1/2m=47.1mV kτm=6.2mV
h1/2 = −60.0 mV kh = −9.0 mV τmaxh=5000ms τ1/2h=60.0mV kτh=9.0mV
ILeak gLeak = N(μleak, σleak) μleak = exp((KBath − 3.425)/4.05) σleak = 0.05 · μleak
ELeak = −26.54 · ln[(PNa · Nain + PK · Kin)/(PNa · Naout + PK · KBath)] PNa = 1 PK = 42
ITonic gTonic = Variable ESyn = 0.0 mV
ISyn gSyn = Dynamic, See Eq. 18 ESyn = 0.0 mV τSyn = 5.0 ms