Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2023 Nov 2:2023.10.31.564805. [Version 1] doi: 10.1101/2023.10.31.564805

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

PMC Copyright notice

Figure 4: — Fut2^−/− mice develop fibrosis and emphysema with elastase administration. A. Hematoxylin and eosin staining of WT and Fut2^−/− mice administered PBS or elastase intratracheally (n = 3). B. Masson’s Trichrome staining indicates increased fibrosis of the alveoli and airways in Fut2^−/− mice (n = 3). C. Fut2^−/− mice have increased total lung capacity and D. residual volume (n = 4 to 9). E. Compliance does not significantly change in Fut2^−/− mice (n = 4 to 9). F. Elastase induces alveolar destruction, measured by mean linear intercept (n = 4 to 6). G. Fut2^−/− mice have undetectable Fut2 transcript in the lung (n = 4-8). H. Hematoxylin and eosin staining of of WT and Fut2^−/− PCLS exposed to air or CS. I. Fut2^−/− PCLS show increased susceptibility to CS as measured by mean linear intercept, which is rescued by reconstitution of Fut2.

Figure 4: — Fut2^−/− mice develop fibrosis and emphysema with elastase administration. A. Hematoxylin and eosin staining of WT and Fut2^−/− mice administered PBS or elastase intratracheally (n = 3). B. Masson’s Trichrome staining indicates increased fibrosis of the alveoli and airways in Fut2^−/− mice (n = 3). C. Fut2^−/− mice have increased total lung capacity and D. residual volume (n = 4 to 9). E. Compliance does not significantly change in Fut2^−/− mice (n = 4 to 9). F. Elastase induces alveolar destruction, measured by mean linear intercept (n = 4 to 6). G. Fut2^−/− mice have undetectable Fut2 transcript in the lung (n = 4-8). H. Hematoxylin and eosin staining of of WT and Fut2^−/− PCLS exposed to air or CS. I. Fut2^−/− PCLS show increased susceptibility to CS as measured by mean linear intercept, which is rescued by reconstitution of Fut2.