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[Preprint]. 2023 Nov 29:2023.10.30.564796. Originally published 2023 Nov 2. [Version 2] doi: 10.1101/2023.10.30.564796

Figure 2. Additional benchmark results using genome-scale Perturb-seq and ECCITE-seq.

Figure 2.

a, Benchmark procedure using a genome-scale Perturb-seq and a published, pooled T cell CRISPR screen. b, The distribution of unstimulated and stimulated Jurkat cells along the UMAP plot. c, The correlation of predicted scores by scMAGeCK-PS and mixscape. d, the Receiver-Operating Characteristic (ROC) curve of both methods in separating positive and negative hits. e-f, Benchmark using a published ECCITE-seq where PDL1 protein expression is used as gold standard (e), and the performance of different methods in terms of predicting PLD1 protein expression (f).