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[Preprint]. 2023 Oct 30:2023.10.29.23297651. [Version 1] doi: 10.1101/2023.10.29.23297651

Figure 5. Overlap of CSF AD Network With Blood Network.

Figure 5.

CSF AD network modules were tested for overlap with serum network modules previously described in Emilsson et al.(24) CSF M33 Oxidant detoxification/MAPK signaling, M26 Neddylation, and M34 Mitochondrion modules significantly overlapped with the serum M11 Lipoprotein module (red box). Many other CSF modules overlapped with serum M27 Axon development/Semaphorin complex and M26 Neuron development/Ephrin signaling modules (blue box). Significance of overlap was determined using overrepresentation analysis and Fisher exact test with Benjamini-Hochberg correction. Red indicates overrepresentation, blue indicates underrepresentation.