Table 1:
Clinical phenotype of subjects used in the study
| iPSCs | Control/Mutation | Disease condition | Age | Sex | iPS cell source | Citation |
|---|---|---|---|---|---|---|
| Ctrl1 | Healthy control | None reported | 69 | F | Blood cells | Hollmann et al., 2020 |
| Ctrl2 (Difficult clone) | Healthy control | None reported | 6 | M | Fibroblasts | Mattis et al., 2012, Le Cann et al., 2021 |
| SFN | Nav1.9 (p.N1169S) and Nav1.8 (p.R923H) variant | Small fiber neuropathy | 69 | F | Fibroblasts | Namer et al., 2019 |
| IEM | Nav1.7 (p.Q875E) | Inherited erythromelalgia | 9 | F | Blood cells | Kalia et al., 2023 (Manuscript in preparation) |
| ANAT001 (RealDRG™) | Healthy control | None reported | Neonatal | F | Blood cells (cord blood derived) | - |