Table 7.
AP characteristics of Ctrl1, IEM and SFN neurons
| Parameters | Ctrl1 | n | IEM | n | SFN | n |
|---|---|---|---|---|---|---|
| RMP, mV | −72.2±1.7 | 12 | −68.8±1.3 | 21 | −69.3±1.1 | 23 |
| Cell capacitance , pF | 19.1±1.7 | 10 | 14.5±0.8 | 17 | 19.6±1.7 | 23 |
| Threshold, pA | 121±16.3 | 10 | 31 1±3.9* | 17 | 47.4±5.3* | 23 |
| AP threshold, mV | −63.1±1.4 | 10 | −58.0±1.0* | 17 | −54.5±0.8* | 23 |
| AHP, mV | −72.1±1.4 | 10 | −75.0±17.0 | 17 | −65.1±0.9* | 23 |
| No. of APs (RAMP stimuli) | 2.6±1.3 | 12 | 5.0±0.8 | 21 | 7.0±1.1* | 23 |
| Time to 1st AP, ms | 143.1±29.0 | 5 | 63 0±5 1 | 20 | 64.5±4.0* | 19 |
Data as Mean ± SEM
*
P<0.05