Figure 6. Differences in excitatory synaptic activity in female insular pyramidal neurons by region.
(A-B) Representative spontaneous excitatory postsynaptic currents (sEPSCs) recorded at −70 mV in female alC and pIC. (C-D) On average, excitatory events are comparable in amplitude and frequency in both alC and pIC. (E-F) Log-normal curve fittings with confidence intervals (± Cl) reveal higher proportion of smaller and more frequent events in the alC as compared to the pIC. Data are presented as box-and-whisker plots (minimum, maximum, median) and analyzed via Mann-Whitney U test. P-values <0.05 are depicted in the graphs. The sample size for alC female was 13/6, and for pIC female was 17/12.
