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[Preprint]. 2023 Oct 28:rs.3.rs-3431502. [Version 1] doi: 10.21203/rs.3.rs-3431502/v1

Figure 7. Differences in inhibitory synaptic activity among male pyramidal neurons in the insular cortex, by region.

Figure 7

(A-B) Representative spontaneous inhibitory postsynaptic currents (sIPSCs) recorded at −70 mV in male alC and pIC. (C-E) Upon conducting a quantitative analysis of the mean amplitude and frequency across these areas, it was found that although the amplitudes were similar, there was a lower frequency of inhibitory events in the pIC when compared to the alC. (E-F) Log-normal curve fittings with confidence intervals (± Cl) reveal that the amplitude and frequency distribution are skewed to the right and to the left respectively in the alC as compared to the pIC. Data are presented as box-and-whisker plots (minimum, maximum, median) and analyzed via Mann-Whitney U test. P-values <0.05 are depicted in the graphs. The sample size for alC male was 22/10, and for pIC male was 14/11.