Table 1.
A. Voltage membrane response per current steps in aIC and pIC pyramidal neurons in both sexes
| Measure (unit) | Condition | Injected current (pA) | aIC | pIC |
p value
Multiple Mann-Whitney Unpaired t test |
||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | SEM | n/N | Mean | SEM | n/N | ||||
| Voltage changes per current step (ΔVm) | Male | −400 | −30.53 | 2.28 | 14/10 | −36.5 | 3.14 | 28/15 | 0.34 |
| −350 | −27.98 | 2.18 | −32.99 | 2.83 | 0.39 | ||||
| −300 | −24.89 | 1.98 | −29.29 | 2.51 | 0.35 | ||||
| −250 | −21.98 | 1.8 | −25.65 | 2.22 | 0.37 | ||||
| −200 | −18.51 | 1.6 | −21.46 | 1.85 | 0.39 | ||||
| −150 | −14.77 | 1.31 | −16.94 | 1.5 | 0.47 | ||||
| −100 | −10.62 | 1 | −12.15 | 1.13 | 0.59 | ||||
| −50 | −5.68 | 0.58 | −6.49 | 0.63 | 0.47 | ||||
| 0 | 0.05 | 0.04 | 0.16 | 0.06 | 0.07 | ||||
| 50 | 7.62 | 1.21 | 8.13 | 0.93 | 0.66 | ||||
| 100 | 15.21 | 1.68 | 14.58 | 1.19 | 0.88 | ||||
| Female | −400 | −28.93 | 1.65 | 13/6 | −37.23 | 1.94 | 20/12 | 0.003 | |
| −350 | −26.19 | 1.6 | −33.91 | 1.78 | 0.001 | ||||
| −300 | −22.97 | 1.21 | −30.23 | 1.61 | 0.002 | ||||
| −250 | −20.08 | 1.2 | −26.34 | 1.43 | 0.003 | ||||
| −200 | −16.75 | 1.1 | −22.33 | 1.28 | 0.003 | ||||
| −150 | −13.31 | 0.86 | −17.74 | 1.1 | 0.006 | ||||
| −100 | −9.3 | 0.62 | −12.68 | 0.86 | 0.01 | ||||
| −50 | −5.01 | 0.38 | −6.85 | 0.55 | 0.02 | ||||
| 0 | 0.09 | 0.08 | 0.21 | 0.15 | 0.34 | ||||
| 50 | 5.52 | 0.47 | 8.74 | 0.97 | 0.07 | ||||
| 100 | 11.92 | 0.99 | 18.63 | 2.57 | 0.02 | ||||