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Extent of neutralization (%) is plotted as a function of NAb concentration (μg/ml). PV was first incubated with Sepharose bead-conjugated PGT145 or PGT151 or mock-depleted with control beads (color-coded legend). Unbound virions were then tested against the indicated NAb or serum in a TZM-bl neutralization assay. The data points in the diagrams are means of 2–4 replicates ± s.e.m.
