Table 2. Comparison of serum components, HbA1c, blood pressure and BMI among the study groups.
Items | High HbA1c | Healthy 1 | p | DM | Healthy 2 | p | |
Fasting glucose a | (mg/dl) | 111.6 ± 34.4 | 94.2 ± 8.3 | *** | 120.1 ± 38.5 | 94.3 ± 8.4 | *** |
HbA1c a | (%) | 6.0 ± 0.8 | 5.0 ± 0.3 | *** | 6.4 ± 1.2 | 5.0 ± 0.3 | *** |
Total cholesterol a | (mg/dl) | 220.2 ± 38.1 | 215.5 ± 37.1 | 209.0 ± 31.6 | 210.4 ± 33.9 | ||
HDL-cholesterol a | (mg/dl) | 55.0 ± 15.7 | 59.0 ± 16.3 | * | 55.6 ± 15.5 | 58.9 ± 17.5 | * |
Triglyceride b | (mg/dl) | 123.3 | 97.5 | *** | 117.9 | 91.7 | *** |
(66.6-264.2) | (54.0-186.3) | (64.6-234.4) | (52.0-173.9) | ||||
TBARS b | (nmol/ml) | 3.17 | 2.91 | ** | 3.08 | 2.90 | |
(2.40-3.82) | (2.30-3.70) | (2.45-3.80) | (2.20-3.60) | ||||
γ-GTP b | (IU/l) | 28.6 | 18.7 | *** | 26.4 | 18.2 | *** |
(12.0-85.4) | ( 9.0-51.0) | (11.0-72.2) | (10.0-46.9) | ||||
SBP a | (mmHg) | 145.9 ± 20.7 | 133.8 ± 19.2 | *** | 141.4 ± 18.7 | 134.9 ± 20.4 | ** |
DBP a | (mmHg) | 85.4 ± 10.7 | 81.4 ± 10.1 | *** | 81.0 ± 11.6 | 80.8 ± 9.7 | |
BMI a | (kg/m2) | 24.8 ± 3.6 | 23.5 ± 2.9 | *** | 24.5 ± 3.3 | 23.2 ± 2.8 | *** |
High HbA1c: the subjects with no history of diabetes mellitus with HbA1c values of 5.6% or more.
DM: the subjects with history of diabetes mellitus.
Healthy1: the healthy control group for High HbA1c group, Healthy2: the healthy control group for DM group.
TBARS: tiobarbituric acid-reactive substances
SBP: systolic blood pressure, DBP: diastolic blood pressure, BMI: body mass index (Weight / [Hight] 2)
a : mean ± standard deviation.
b : geometric mean and range of 10-90% in parenthesis.
p: t test (*:p<0.05, **: p<0.01, ***: p<0.001)