Table 1.
Clinical and CMR Characteristics in Patients With Breast Cancer and Healthy Control Women
| Healthy (n = 17) | Coefficient of Variations | Cancer (n = 28) | Coefficient of Variations | P Value | |
|---|---|---|---|---|---|
| Clinical characteristics | |||||
| Age, y | 59 ± 8.4 | 14.27 | 52.5 ± 10.2 | 19.56 | 0.14 |
| Systolic blood pressure, mm Hg | 125.5 ± 15.2 | 12.12 | 130 ± 15 | 11.55 | 0.36 |
| Diastolic blood pressure, mm Hg | 74.4 ± 7.7 | 10.45 | 71.5 ± 9.7 | 13.65 | 0.32 |
| Heart rate, beats/min | 68.75± 10.29 | 14.97 | 79.6 ± 13.05 | 16.40 | 0.006 |
| Big endothelin-1, pg/mL | 2.9 ± 0.47 | 15.88 | 3.4 ± 0.48 | 14.49 | 0.014 |
| CMR characteristics | |||||
| Indexed cardiac volumes and mass | |||||
| LVEDV, mL/m2 | 73.9 ± 12.4 | 16.95 | 85.6 ± 19 | 22.28 | 0.031 |
| LVESV, mL/m2 | 28.4 ± 4.9 | 17.52 | 33.7 ± 9.3 | 27.77 | 0.038 |
| LV stroke volume, mL/m2 | 45.5 ± 9.3 | 20.51 | 51.9 ± 12.4 | 23.96 | 0.076 |
| LVEF, % | 61.4 ± 4.5 | 7.463 | 60.8 ± 6.4 | 10.53 | 0.73 |
| LV mass, g/m2 | 50.7 ± 7.6 | 14.99 | 61.1 ± 9.4 | 15.54 | <0.001 |
| RVEDV, mL/m2 | 68.1 ± 16.7 | 24.63 | 84 ± 22.9 | 27.29 | 0.017 |
| RVESV, mL/m2 | 28.9 ± 8.1 | 28.26 | 32 ± 11.2 | 35.13 | 0.34 |
| RV stroke volume, mL/m2 | 40.5 ± 8.1 | 19.99 | 52.01 ± 13.9 | 26.75 | 0.027 |
| RVEF, % | 58.5 ± 6.2 | 10.72 | 62.4 ± 7.08 | 11.36 | 0.069 |
| LAV, mL/m2 | 44.6 ± 12.5 | 28.11 | 50.9 ± 14.2 | 28.03 | 0.14 |
| Global longitudinal strain | |||||
| LV GLS endocardial, % | −21.8 ± 2.3 | 10.99 | −20.37 ± 2.4 | 11.80 | 0.055 |
| LV GLS midwall, % | −21.7 ± 2.2 | 10.40 | −20.38 ± 2.4 | 11.94 | 0.073 |
| LV GLS epicardial, % | −18.37 ± 2.25 | 12.26 | −17.2 ± 12.3 | 13.59 | 0.11 |
| LV GLS average, % | −20.6 ± 2.2 | 10.71 | −19.3 ± 2.34 | 12.13 | 0.068 |
Values are mean ± SD or %.
Some results presented in this Table have been previously reported.9
CMR = cardiac magnetic resonance; GLS = global longitudinal strain; LAV = left atrial volume; LV = left ventricular; LVEDV = left ventricular end-diastolic volume; LVEF = left ventricular ejection fraction; LVESV = left ventricular end-systolic volume; RV = right ventricular; RVEDV = right ventricular end-diastolic volume; RVEF = right ventricular ejection fraction; RVESV = right ventricular end-systolic volume.