Fig. 6.

GRg1 promotes the expression of miR-216a-5p and inhibits the TLR4/NF-kB signaling pathway to affect growth factors and inflammatory cytokines in retinal microvascular endothelial cells. A: The levels of TLR4/NF-kB-related proteins were detected by Western blotting. B: Cell proliferation was detected by BrdU staining. C: The cell cycle was detected by flow cytometry. D: Angiogenesis was detected by tubule formation experiments. E: The levels of TNF-α, IL-6 and IL-1β were detected by ELISA. F: The levels of VEGF, FGF and PDGF by were detected Western blotting. *P<0.05, **P<0.01, ***P<0.001