Table 3.

Definition of modalities used in the ROC analysis.

Modality name	Description
PSMA	SUVmax [g/ml] per lesion for [68Ga]PSMA-11
ACE	SUVmax [g/ml] per lesion for [11C]Acetate
$\tilde{\text{K}}$trans	Maximum Ktrans [min−1] per lesion, divided by the mean Ktrans in the non-malignant PZ of the patient
$\widetilde{\text{ADC}}$	Median ADC [µm2 s−1] per lesion, divided by the mean ADC in the non-malignant PZ of the patient
$\widetilde{\text{T}2}$	Median image intensity per lesion in the T2w image, divided by the mean image intensity in the non-malignant PZ of the patient

ROC receiver operating characteristic, PSMA prostate-specific membrane antigen, SUV_max maximum standardized uptake value, K^trans volume transfer constant, ADC apparent diffusion coefficient, T2w T2-weighted, PZ peripheral zone.

Tilde signifies a ratio, making these quantities unitless.